RESEARCH

Mafalda is fascinated by how tiny things such as viruses, bacteria, or mutations in our DNA cause illnesses.

After a brief period working in biotechnology, she started studying the effects of a potential anti-cancer drug in the mitochondrial metabolism of hepatocarcinoma (liver cancer) cells. Then, Mafalda's PhD research was focused on understanding how a family of viruses, called Flaviviruses, are able to exploit the cellular machinery and escape its innate immune response.

ACADEMIC JOURNEY

GUEST LECTURER

Instituto Politécnico de Setúbal

Lavradio, Portugal
2019 - 2021

Chemistry and Biology Section

Courses lectured: Biochemistry, Analytical Chemistry, and Microbiology.

PHD IN VIRUS-HOST INTERACTIONS

University of Surrey
Guildford, United Kingdom
2016 - 2020

Department of Biochemical Sciences, Immunology Section

Supervised by Dr Peter Mayerhofer, Dr Rachel Simmonds, and Dr. Kevin Maringer.

Thesis title: "Role of peroxisomes and PEX19 in Zika and dengue virus-host interactions".

RESEARCH INTERNSHIP

Academic Medical Centre, University of Amsterdam
Amsterdam, Netherlands
September 2014 - December 2014
Laboratory Genetic Metabolic Diseases

Supervised by Dr Ronald JA Wanders.

MASTERS DEGREE IN BIOPHARMACEUTICAL SCIENCES

Faculty of Pharmacy, University of Lisbon

Lisbon, Portugal

2013-2015

Drug discovery - Metabolism and Genetics

Supervised by Dr Margarida FB Silva (FFUL, UL) and Dr Ronald JA Wanders (AMC, UvA).

Thesis title: "The role of a KDAC inhibitor in nitrogen metabolism: the therapeutic challenges for liver disease and hepatocellular carcinoma."

SCIENTIFIC RESEARCH TRAINING COURSE

Institute of Chemistry and Biologic Technology (ITQB)

Oeiras, Portugal

September 2012 - March 2013

Plant Cell Biology Laboratory

Supervised by Dr Rita Abranches.

Project title: "Establishment of cell suspension cultures of Medicago truncatula expressing human recombinant L-PGDS enzyme by transformation mediated by Agrobacterium tumefaciens."

BACHELOR IN CELLULAR AND MOLECULAR BIOLOGY

Faculty of Sciences and Technology (FCT), New University of Lisbon (UNL)
Almada, Portugal
2009-2013


ACADEMIC WRITING

Below is the collection of published scientific papers to which I am an author.

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Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS.

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Drug-induced effects on urea cycle enzymes associate with altered ammonia metabolism,  NAD+ biosynthesis and mitochondrial protein acetylome.

TECHNICAL WRITING

Below is the collection of published technical writing pieces to which I am an author.

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Mass spectrometry at the forefront of the COVID-19 pandemic.

Ebook - The Role of Mass Spectrometry in Virus Research.
Chapter 3: An Introduction to Mass Spectrometry in Virus-Host Interactions.